The Molecular Industrial Revolution: Automated Synthesis of Small Molecules

The Molecular Industrial Revolution: Automated Synthesis of Small Molecules.

Today we are poised for a transition from the highly customized crafting of specific molecular targets by hand to the increasingly general and automated assembly of different types of molecules with the push of a button. Creating machines that are capable of making many different types of small molecules on demand, akin to that which has been achieved on the macroscale with 3D printers, is chal...

The New Industrial Revolution

The New Industrial Revolution

This article outlines a new framework for understanding the current period of global restructuring, focusing on the relationship between technological change and organizational change. After reviewing the major approaches in the debate over future pathways to industrialization, a new perspective for understanding the ‘new industrial revolution’ is presented. At the core of this revolution is th...

The British Industrial Revolution

ORGANIC SYNTHESIS Synthesis of many different types of organic small molecules using one automated process

Small-molecule synthesis usually relies on procedures that are highly customized for each target. A broadly applicable automated process could greatly increase the accessibility of this class of compounds to enable investigations of their practical potential. Here we report the synthesis of 14 distinct classes of small molecules using the same fully automated process. This was achieved by strat...